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    Articles in press have been peer-reviewed and accepted, which are not yet assigned to volumes /issues, but are citable by Digital Object Identifier (DOI).
    Comparing the spatial transcriptomic difference of the protective effect between Panax notoginseng and Panax ginseng against acute stroke with Spatial-seq 2.0
    Guoqian Cui, Renjie Chen, Yining Hu, Qikun Zhao, Hudong Bao, Shujun Xu, Shiyan Qian, Wenbo Guo, Xiaohui Fan, Jie Liao
    DOI: 10.48130/targetome-0026-0038
    Immunosenescence-Driven Bone Marrow Immune Niche Destabilization in Osteoporosis: Microenvironmental Targets and Natural Product-Mediated Reprogramming
    Yan Duan, Liu-ye Li, Qin-zhe Lou, Yu-yuan Liao, Juan Li, Shun-xiang Li
    DOI: 10.48130/targetome-0026-0040
    KCC2 neuromodulation remodels metabolic and morphofunctional signatures across the neuromuscular axis in mdx mice
    Alex D Assis, Iola MF Duarte, Alessandra Sussulini, Alexandre LR Oliveira
    DOI: 10.48130/targetome-0026-0041
    From Molecular Markers to Architectural Control: Cytoskeletal Checkpoints as the Decisive State-Access Layer of the Aging Microglial Targetome
    Inês Mendes Pinto, Pedro Beça, Miguel Correia, Joana T. Moreira, João Galvão, Camila C. Portugal, João B. Relvas, Renato Socodato
    DOI: 10.48130/targetome-0026-0035
    Design and delivery of targeting chimeras therapeutics in managing central nervous system disorders
    Shuo Liu, Wei Xu, Mengxi Wang, Zhen Mao, Jianping Zhou, Xiaochen Gu, Guochen Han, Yang Ding
    DOI: 10.48130/targetome-0026-0028
    Drug resistance-driven cytokine alterations in the immunosuppressive microenvironment of colorectal cancer
    Yingying Shao, Zewen Zhang, Yu Wang, Chunze Zhang, Erwei Liu, Haiyang Yu
    DOI: 10.48130/targetome-0025-0012
    Molecular characteristics, regulatory mechanisms, and targeted therapeutic strategies of Claudin18.2 in pancreatic cancer
    Xiaoying Pan, Xinyuan Cao, Jiaojiao Ni, Jieer Ying
    2026, 2(4): e034. DOI: 10.48130/targetome-0026-0033
    An AI-integrated pharmacophore and transcriptomic framework for rapid discovery of therapeutic leads for ischemic stroke
    Jinran Li, Zheng Zhou, Yongjun Zhao, Sai Liu, Long Chen, Yiting Shi, Haotian Li, Yuan Sun, Tingting Yao, Wei Jiang, Qun Xue, Zheying Zhu, Guangji Wang, Xinuo Li
    2026, 2(4): e035. DOI: 10.48130/targetome-0026-0034
    A photo-clickable, chain-terminating NAD+ analogue enables systematic profiling of the PAR-interacting proteome under oxidative stress
    Lijuan Gao, Zhenlin Tu, Yangyang Zhou, Yanhui Xu, Yueqi Sun, Tianye Dai, Jinbo Zhan, Mengwei Li, Xiao-Nan Zhang
    2026, 2(4): e031. DOI: 10.48130/targetome-0026-0030
    From target fishing to AI and single-cell multi-omics: an integrated framework for natural product target research
    Haojie Du, Nana Chen, Yang Sun
    2026, 2(4): e037. DOI: 10.48130/targetome-0026-0036
    Drugging the efferocytosis process for treating hepatic fibrosis: dual roles, mechanisms, and therapeutics
    Yaning Chen, Yingyin Sun, Xin Chen, Yuchen Liu, Hua Wang
    2026, 2(4): e032. DOI: 10.48130/targetome-0026-0031
    Molecular pharmacotargets in donor cardiac graft preservation: mechanisms and translational perspectives
    Chenchen Sun, Xiangwang Zhao, Jiangyang Chi, Yonghui Zhang, Zhengxi Hu
    2026, 2(4): e036. DOI: 10.48130/targetome-0026-0039
    Nesprin-2-mediated epigenetic remodeling under mechanical load: anti-tumor mechanisms and strategies
    Fangfang Liu, Jinjian Lu
    2026, 2(4): e033. DOI: 10.48130/targetome-0026-0032
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