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Data-driven targetome discovery and database requirements: insights from the therapeutic target database
Wenying Shan, Jianzhen Xu, Yehuda G. Assaraf
2026, 2(1): e003. DOI: 10.48130/targetome-0026-0001
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Multi-omics integration identifies MT2A as a biomarker and a candidate host target linking zinc dysregulation to COVID-19 mortality
Zhonghua Li, Siqi Hua, Shuangshuang Song, Yixiang Luo, Wei Qian, Lina Liu, Jiahuang Li, Bo Zhu
2026, 2(1): e006. DOI: 10.48130/targetome-0026-0006
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Proteome-wide dose-response measurements for the characterization of drug mechanism of action
Nicola Berner, Florian P. Bayer, Amy George, Nicole Kabella, F. Luna Bergamasco, Bernhard Kuster
2026, 2(1): e001. DOI: 10.48130/targetome-0025-0011
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Cell-type-specific role of cullin 3 in adipocytes and hepatocytes: metabolic implications of neddylation inhibition
Ziqiao Yuan, Ziwei Wang, Tingting Qin, Bin Yu
2026, 2(1): e002. DOI: 10.48130/targetome-0025-0013
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TGFβ3-SMAD2/ETV4/CARM1 axis drives metastatic progression in Muscle-invasive Bladder Cancer via succinate metabolic rewiring
Miaoling Tang, Meisongzhu Yang, Rongni Feng, Jinbin Lin, Xiaohong Chen, Hequn Zou, Changhao Chen, Libing Song, Jun Li
2026, 2(1): e008. DOI: 10.48130/targetome-0026-0007
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Anti-amyloid antibody therapies for Alzheimer's disease: how much do we really understand?
Yun Chen
2026, 2(1): e004. DOI: 10.48130/targetome-0026-0004
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Xuebijing injection ameliorates LPS-mediated acute lung injury via multi-target synergy by alleviating inflammation and ferroptosis
Siwen Hui, Xinyuan Li, Xinchi Feng, Xinrong Xu, Huilin Zhang, Zhiqiao Feng, Qing Xia, Yaxue Jia, Feng Qiu, Juan Zhang, Chengpeng Sun
2026, 2(1): e005. DOI: 10.48130/targetome-0026-0005
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An iron sensor-based approach discovers a role for epigenetic regulation in iron homeostasis
Yang Zhang, Tracey A. Rouault
2026, 2(1): e007. DOI: 10.48130/targetome-0026-0008
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